Preventing Illegal Laboratories and Protecting Public Health Act of 2026

#4227 | S Congress #119

Subjects:

Last Action: Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (3/26/2026)

Bill Text Source: Congress.gov

Summary and Impacts
Original Text

Bill Summary

The "Preventing Illegal Laboratories and Protecting Public Health Act of 2026" is a piece of legislation aimed at enhancing the regulation of highly pathogenic agents, which are biological agents posing significant health risks. The Act mandates that the Secretary of Health and Human Services, through the Assistant Secretary for Preparedness and Response, implement a comprehensive program to ensure that distributors of these agents maintain detailed logbooks documenting all sales, leases, loans, and other transfers.

Key provisions include:

1. **Logbook Requirements**: Covered distributors must keep an electronic logbook detailing the transaction of highly pathogenic agents, including the purchaser's information, intended use, and transfer details.

2. **List of Agents**: The Secretary is tasked with developing and regularly updating a list of agents classified as highly pathogenic, based on established guidelines and expert consultations.

3. **Compliance and Audits**: The Secretary will have the authority to conduct audits to ensure compliance with logbook requirements, focusing on higher-risk distributors.

4. **False Statements**: The Act stipulates that providing false information for logbook entries may lead to criminal penalties.

5. **Evaluation of Laboratories**: The legislation also mandates a strategic evaluation of high-containment laboratories in the U.S. to assess their security, capacity, and potential risks, with the establishment of a dedicated team to oversee biosafety and biosecurity issues.

Overall, the act seeks to strengthen oversight of potentially dangerous biological materials to protect public health and prevent illegal laboratory operations.

Possible Impacts

The "Preventing Illegal Laboratories and Protecting Public Health Act of 2026" could affect people in the following ways:

1. **Increased Safety and Transparency in Handling Pathogenic Agents**: The legislation mandates that covered distributors of highly pathogenic agents maintain detailed logbooks of all transactions involving these agents. This requirement aims to enhance accountability and traceability, which can help prevent the mishandling or illegal distribution of dangerous pathogens, ultimately protecting public health. Individuals may feel more secure knowing that there are stringent regulations governing the sale and transfer of potentially harmful biological agents.

2. **Legal Consequences for Non-compliance**: The act stipulates that providing false information in logbooks can lead to criminal penalties. This provision could lead to individuals or organizations facing legal repercussions if they fail to comply with the law. As a result, participants in the scientific and medical fields may need to invest more time and resources into ensuring compliance with these regulations, affecting their operations and possibly leading to increased costs.

3. **Impact on Research Institutions and Laboratories**: The evaluation and oversight of high-containment laboratories are emphasized in the legislation. As a result, research institutions may face additional scrutiny and administrative burdens to comply with new oversight measures, which could impact their funding and ability to conduct research involving highly pathogenic agents. This could lead to delays in research projects, affecting scientists, students, and the broader community that relies on advancements in biomedical research and public health initiatives.

[Congressional Bills 119th Congress]
[From the U.S. Government Publishing Office]
[S. 4227 Introduced in Senate (IS)]

<DOC>






119th CONGRESS
  2d Session
                                S. 4227

 To require the Secretary of Health and Human Services, acting through 
 the Assistant Secretary for Preparedness and Response, to carry out a 
program under which the Secretary requires each covered distributor of 
a highly pathogenic agent to comply with certain logbook requirements, 
                        and for other purposes.


_______________________________________________________________________


                   IN THE SENATE OF THE UNITED STATES

                             March 26, 2026

 Ms. Cortez Masto (for herself and Mr. Banks) introduced the following 
  bill; which was read twice and referred to the Committee on Health, 
                     Education, Labor, and Pensions

_______________________________________________________________________

                                 A BILL


 
 To require the Secretary of Health and Human Services, acting through 
 the Assistant Secretary for Preparedness and Response, to carry out a 
program under which the Secretary requires each covered distributor of 
a highly pathogenic agent to comply with certain logbook requirements, 
                        and for other purposes.

    Be it enacted by the Senate and House of Representatives of the 
United States of America in Congress assembled,

SECTION 1. SHORT TITLE.

    This Act may be cited as the ``Preventing Illegal Laboratories and 
Protecting Public Health Act of 2026''.

SEC. 2. REQUIRING CERTAIN DISTRIBUTORS OF HIGHLY PATHOGENIC AGENTS TO 
              KEEP A LOGBOOK OF SALES, LEASES, LOANS, AND OTHER 
              TRANSFERS.

    (a) Program.--The Secretary shall carry out a program under which 
the Secretary requires each covered distributor of a highly pathogenic 
agent to comply with the logbook requirements of subsection (c).
    (b) List of Highly Pathogenic Agents.--
            (1) Development.--The Secretary shall develop and maintain 
        a list of all agents that meet the definition of a highly 
        pathogenic agent in subsection (e).
            (2) Initial list.--The Secretary shall develop the initial 
        list required by paragraph (1) not later than 6 months after 
        the date of enactment of this Act.
            (3) Periodic review.--The Secretary shall annually review 
        and update the list required by paragraph (1).
            (4) Consultation; consideration.--In developing and 
        updating the list required by paragraph (1), the Secretary 
        shall--
                    (A) consult with relevant agencies, including the 
                Centers for Disease Control and Prevention, the 
                National Institutes of Health, the Department of 
                Homeland Security, the Department of Agriculture, the 
                Department of the Interior, and the Department of 
                Defense;
                    (B) take into consideration the latest edition of 
                ``Biosafety in Microbiological and Biomedical 
                Laboratories'' published by the Centers for Disease 
                Control and Prevention and the National Institutes of 
                Health (or any successor to such publication); and
                    (C) take into consideration the latest edition of 
                ``NIH Guidelines for Research Involving Recombinant or 
                Synthetic Nucleic Acid Molecules'' published by the 
                National Institutes of Health (or any successor to such 
                publication).
    (c) Logbook Requirements.--
            (1) In general.--Each covered distributor shall maintain, 
        in accordance with such criteria and format as the Secretary 
        may require, an electronic list (in this section referred to as 
        a ``logbook'') of the sales, leases, loans, or other transfers 
        by such distributor of each highly pathogenic agent on the list 
        under subsection (b).
            (2) Contents.--The covered distributor shall, for each 
        sale, lease, loan, or other transfer referred to in paragraph 
        (1), include in the logbook--
                    (A) the agent by name;
                    (B) the name, address, telephone number, and email 
                address of the purchaser;
                    (C) other relevant identifying business information 
                of the purchaser, as the Secretary determines 
                appropriate;
                    (D) a short description of--
                            (i) the purchaser's intended use of the 
                        highly pathogenic agent; and
                            (ii) where the purchaser will house the 
                        agent;
                    (E) the date and time of the sale, lease, loan, or 
                other transfer;
                    (F) the method, date, and time of transfer of the 
                highly pathogenic agent;
                    (G) a physical or electronic signature of the 
                purchaser; and
                    (H) such other data elements as the Secretary may 
                require.
            (3) Sale requirements.--In the case of a sale, lease, loan, 
        or other transfer to which paragraph (1) applies, the covered 
        distributor shall not sell the highly pathogenic agent unless--
                    (A) the prospective purchaser, in physical form or 
                electronically in compliance with the Electronic 
                Signatures in Global and National Commerce Act (42 
                U.S.C. 7001 et seq.)--
                            (i) presents an identification card that 
                        provides a photograph and is issued by a State 
                        or the Federal Government, or a document that, 
                        with respect to identification, is considered 
                        acceptable for purposes of sections 
                        274a.2(b)(1)(v)(A) and 274a.2(b)(1)(v)(B) of 
                        title 8, Code of Federal Regulations (or 
                        successor regulations); and
                            (ii) verifies by signature in the logbook--
                                    (I) the purchaser's name and 
                                address;
                                    (II) a short description of--
                                            (aa) the purchaser's 
                                        intended use of the agent; and
                                            (bb) where the purchaser 
                                        will house the agent;
                                    (III) the date and time of the 
                                sale, lease, loan, or other transfer; 
                                and
                                    (IV) the method, date, and time of 
                                transfer of the agent; and
                    (B) the covered distributor--
                            (i) determines that the name entered in the 
                        logbook corresponds to the name provided on the 
                        identification card described in subparagraph 
                        (A)(i), and that the information entered 
                        pursuant to subparagraph (A)(ii) is correct; 
                        and
                            (ii) enters in the logbook the name of the 
                        highly pathogenic agent.
            (4) Notice.--The covered distributor shall include in the 
        logbook, in accordance with criteria of the Secretary, a notice 
        to purchasers that entering false statements or 
        misrepresentations in the logbook may subject the purchasers to 
        criminal penalties under section 1001 of title 18, United 
        States Code, which notice specifies the maximum fine and term 
        of imprisonment under such section.
            (5) Duration of maintenance of entries.--
                    (A) Retention period.--The covered distributor 
                shall maintain each entry in the logbook for not fewer 
                than 3 years after the date on which the entry is made.
                    (B) Successor entity.--If ownership of a covered 
                distributor changes, the successor entity shall assume 
                custody of and responsibility for all logbooks for the 
                remainder of the 3-year retention period required by 
                subparagraph (A).
            (6) Disclosure of logbooks.--The Secretary shall establish 
        restrictions on disclosure of information in logbooks. Such 
        regulations shall--
                    (A) provide for the disclosure of the information, 
                as appropriate, to the Secretary, Federal, State, 
                local, Tribal, and territorial law enforcement 
                agencies, and State health officials; and
                    (B) prohibit accessing, using, or sharing 
                information in the logbooks for any purpose other 
                than--
                            (i) to ensure compliance with this section;
                            (ii) to protect public health and safety; 
                        or
                            (iii) to protect national security.
            (7) FOIA exemption.--Logbooks and any derivative data are 
        exempt from disclosure under section 552(b)(3) of title 5, 
        United States Code.
            (8) Applicability.--A transfer of a highly pathogenic agent 
        between laboratories within a single institution of higher 
        education (as defined in section 101 of the Higher Education 
        Act of 1965 (20 U.S.C. 1001)) does not constitute a sale, 
        lease, loan, or other transfer of the agent for purposes of 
        paragraph (1).
            (9) Audits.--The Secretary shall establish a risk-based 
        compliance review process by which the Secretary may conduct 
        audits of logbooks when the Secretary has cause to believe a 
        violation of this section has occurred. The Secretary shall 
        focus audits conducted under this paragraph on higher-risk 
        distributors and suspicious patterns.
    (d) False Statements or Misrepresentations by Purchasers.--For 
purposes of section 1001 of title 18, United States Code, providing 
information to a covered distributor for purposes of entering such 
information in a logbook shall be considered a matter within the 
jurisdiction of the executive, legislative, or judicial branch of the 
Government of the United States.
    (e) Definitions.--In this section:
            (1) The term ``covered distributor''--
                    (A) means an entity that sells, leases, loans, or 
                otherwise transfers for value or not for value a highly 
                pathogenic agent, except that such term does not 
                include an employee or agent of such a distributor; and
                    (B) includes a publicly funded repository or 
                biobank that sells, leases, loans, or otherwise 
                transfers a highly pathogenic agent, as described in 
                subparagraph (A).
            (2) The term ``highly pathogenic agent''--
                    (A) subject to subparagraph (B), means a pathogenic 
                agent that meets the criteria of ``risk group 3'' or 
                any higher level risk groups as such risk groups are 
                defined in the latest edition of ``NIH Guidelines for 
                Research Involving Recombinant or Synthetic Nucleic 
                Acid Molecules'' published by the National Institutes 
                of Health (or any successor to such publication); and
                    (B) excludes any biological agent or toxin that is 
                regulated under section 351A of the Public Health 
                Service Act (42 U.S.C. 262a) or section 212 of the 
                Agricultural Bioterrorism Protection Act of 2002 (7 
                U.S.C. 8401).
            (3) The term ``Secretary'' means the Secretary of Health 
        and Human Services, acting through the Assistant Secretary for 
        Strategic Preparedness and Response.
    (f) Rule of Construction.--Nothing in this section shall be 
construed to supersede or otherwise affect the Federal Select Agent 
Program under section 351A of the Public Health Service Act (42 U.S.C. 
262a) and section 212 of the Agricultural Bioterrorism Protection Act 
of 2002 (7 U.S.C. 8401).

SEC. 3. EVALUATION OF HIGH-CONTAINMENT LABORATORIES.

    (a) In General.--The National Security Advisor, in consultation 
with the Secretary of Health and Human Services, the Secretary of 
Agriculture, the Secretary of Defense, the Secretary of Homeland 
Security, the Secretary of the Interior, the Director of National 
Intelligence, and such other Federal officials as the National Security 
Advisor determines appropriate, shall identify a single Federal entity 
to oversee a periodic strategic evaluation of high-containment 
laboratories in the United States.
    (b) Topics.--Each strategic evaluation under subsection (a) shall 
include--
            (1) an assessment of--
                    (A) the number, location, and mission of high-
                containment laboratories;
                    (B) the capacity of such existing laboratories to 
                effectively meet national goals to counter threats to 
                biosafety and biosecurity;
                    (C) the physical security measures at high-
                containment laboratories;
                    (D) the aggregate risks associated with--
                            (i) such existing laboratories; and
                            (ii) expanding the numbers and facilities 
                        of such laboratories; and
                    (E) the type of oversight needed for high-
                containment laboratories; and
            (2) up-to-date national standards, developed by the Federal 
        entity identified under subsection (a), that--
                    (A) are developed by the Federal entity identified 
                under subsection (a) in consultation with members of 
                the scientific community, for the design, construction, 
                commissioning, operation, and long-term maintenance of 
                high-containment laboratories; and
                    (B) take into consideration applicable regulations 
                and guidance for high-containment laboratories.
    (c) Reporting.--Upon completion of each strategic evaluation under 
subsection (a), the Federal entity identified under subsection (a) 
shall submit to the President and to Congress a report on the results 
of such evaluation and include in each such report recommendations on--
            (1) addressing gaps in Federal oversight of high-
        containment laboratories; and
            (2) utilizing high-containment laboratories for protecting 
        public health and ensuring biosafety and biosecurity in the 
        United States.
    (d) Public Health Biosafety and Biosecurity Team.--
            (1) In general.--The Federal entity identified under 
        subsection (a) shall maintain a team, to be known as the Public 
        Health Biosafety and Biosecurity Team, to serve as a single 
        point of contact for State, local, Tribal, and territorial 
        agencies regarding questions relating to laboratory biosafety 
        and biosecurity.
            (2) Establishment.--The Federal entity identified under 
        subsection (a) shall establish the Public Health and 
        Biosecurity Team, as required by paragraph (1), not later than 
        one year after such official is first designated.
            (3) Duties.--The Public Health Biosafety and Biosecurity 
        Team shall be the single point of contact in the Federal 
        Government for State, local, Tribal, and territorial agencies 
        on--
                    (A) issues related to--
                            (i) oversight of high-containment 
                        laboratories;
                            (ii) the impact of high-containment 
                        laboratories on public health; or
                            (iii) connecting State, local, Tribal, and 
                        territorial officials with the relevant Federal 
                        agency or agencies on matters related to high-
                        containment laboratories; and
                    (B) other issues as the Federal entity identified 
                under subsection (a) determines appropriate.
    (e) Feasibility Study.--
            (1) In general.--The Federal entity identified under 
        subsection (a) shall conduct a feasibility study on 
        establishing and maintaining a database on existing high-
        containment laboratories in the United States for the purpose 
        of making such database accessible to Federal, State, local, 
        Tribal, and territorial officials.
            (2) Database described.--The database considered under 
        paragraph (1) shall be a database designed to include, with 
        respect to each high-containment laboratory, the following 
        information:
                    (A) The identity of the owners of the laboratory.
                    (B) The address of the laboratory.
                    (C) The status of any licensing or certification of 
                the laboratory required under Federal, State, local, 
                Tribal, or territorial law.
                    (D) Any legal violations by, and disciplinary 
                action taken against, the laboratory.
                    (E) Such additional information as the Federal 
                entity identified under subsection (a) determines 
                appropriate to protect biosafety and biosecurity.
            (3) Report to congress.--Upon completion of the feasibility 
        study under this subsection, the Federal entity identified 
        under subsection (a) shall submit to Congress a report on the 
        results of such study.
    (f) Definition.--In this section, the term ``high-containment 
laboratory'' means a laboratory that is suitable for ``biosafety level 
3'' or any higher biosafety level procedures, as defined in the latest 
edition of ``Biosafety in Microbiological and Biomedical Laboratories'' 
published by the Centers for Disease Control and Prevention and the 
National Institutes of Health (or any successor to such publication).
                                 <all>